Endocrine Abstracts

Case: A 46-year-old woman presented to the gynaecology department with secondary amenorrhoea, hirsutism and acne. At the age of 25, she was diagnosed with Von Hippel–Lindau disease (VHLD) on the basis of multiple right retinal haemangioblastomas. Investigation revealed an elevated testosterone 13.4 nmol/l (0.3–2.6 nmol/l), 17 hydroxyprogesterone 18 nmol/l and free androgen index 53.6 (0.0–7.5). A solid lesion in the left ovary was demonstrated on ultrasound scan...

A 70-year-old lady with known hypothyroidism and ischaemic heart disease (previous CABG) presented with tonic clonic seizures. Her BP was 245/110. She was admitted to the intensive care unit. MRI brain showed subcortical oedema with subarachnoid bleed in the left temporal parietal region. Investigation for malignant hypertension showed a solid mass measuring 17×17×11 cm completely replacing the left kidney on CT-scanning. She was discharged home on sodium valproate w...